Akito Tsutsumi Selected Research

Systemic Lupus Erythematosus (Libman-Sacks Disease)

3/2011	Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus.
2/2009	Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.
6/2007	Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosus.
1/2007	Successful treatment of refractory thrombotic thrombocytopenic purpura with cyclosporine and corticosteroids in a patient with systemic lupus erythematosus and antibodies to ADAMTS13.
1/2006	Significance of antiprothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluation of the antiprothrombin assay and the antiphosphatidylserine/prothrombin assay, and comparison with other antiphospholipid antibody assays.
1/2005	Lack of relationship between mannose-binding lectin variant alleles and risk of arterial thrombosis in Japanese patients with systemic lupus erythematosus.
4/2004	Polymorphisms of IL-1 beta gene in Japanese patients with Sjögren's syndrome and systemic lupus erythematosus.
12/2003	Low expression levels of soluble CD1d gene in patients with rheumatoid arthritis.

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Akito Tsutsumi Research Topics

Disease

17	Rheumatoid Arthritis 05/2021 - 03/2003
10	Arthritis (Polyarthritis) 03/2008 - 01/2004
8	Systemic Lupus Erythematosus (Libman-Sacks Disease) 03/2011 - 12/2003
5	Autoimmune Diseases (Autoimmune Disease) 06/2007 - 03/2003
3	Osteoarthritis 08/2006 - 06/2004
3	Thrombosis (Thrombus) 01/2006 - 06/2002
2	Thrombotic Thrombocytopenic Purpura 01/2013 - 01/2007
2	Synovitis 11/2005 - 09/2005
1	Osteoporosis 05/2021
1	Connective Tissue Diseases (Connective Tissue Disease) 01/2013
1	Mixed Connective Tissue Disease (MCTD) 01/2013
1	Pericardial Effusion 01/2013
1	Periodontitis 02/2009
1	Chronic Periodontitis 02/2009
1	Nephritis 01/2008
1	Sjogren's Syndrome (Sjogren Syndrome) 06/2007
1	Seizures (Absence Seizure) 01/2007
1	Anemia 01/2007
1	Hypoalbuminemia 01/2007
1	Hypergammaglobulinemia (Hyperimmunoglobulinemia) 01/2007
1	Coma (Comas) 01/2007
1	Multi-centric Castleman's Disease 01/2007
1	Castleman Disease (Castleman's Disease) 01/2007
1	Fever (Fevers) 01/2007
1	Fatigue 01/2007
1	Dermatomyositis (Dermatopolymyositis) 01/2006
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2006
1	Polymyositis 01/2006
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2006
1	Reactive Arthritis (Reiter Disease) 01/2004
1	Conjunctivitis 01/2004
1	Urethritis 01/2004
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2004

Drug/Important Bio-Agent (IBA)

9	AntibodiesIBA 01/2008 - 10/2004
5	IsomerasesIBA 08/2007 - 01/2005
4	thiamine triphosphorate (TTP)IBA 01/2013 - 06/2004
4	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 02/2009 - 01/2005
4	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 03/2008 - 10/2004
4	TristetraprolinIBA 01/2008 - 06/2004
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2008 - 06/2004
4	AntigensIBA 07/2007 - 03/2003
4	AutoantibodiesIBA 06/2007 - 01/2005
3	Monoclonal AntibodiesIBA 03/2008 - 01/2008
3	DNA (Deoxyribonucleic Acid)IBA 01/2008 - 12/2003
3	C-Reactive ProteinIBA 06/2007 - 10/2003
3	Complementary DNA (cDNA)IBA 08/2006 - 06/2004
3	EnzymesIBA 01/2006 - 10/2004
3	Immunoglobulin G (IgG)IBA 01/2006 - 09/2005
2	Interleukin-17 (Interleukin 17)IBA 03/2008 - 01/2008
2	Interleukin-6 (Interleukin 6)IBA 03/2008 - 01/2008
2	CytokinesIBA 03/2008 - 01/2008
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2008 - 03/2003
2	Immunoglobulins (Immunoglobulin)IBA 01/2008 - 11/2005
2	Peptides (Polypeptides)IBA 01/2008 - 01/2006
2	T-Cell Intracellular Antigen-1IBA 07/2007 - 08/2006
2	HLA-DRB1 Chains (HLA DRB1)IBA 01/2006 - 03/2003
2	Collagen Type II (Type II Collagen)IBA 01/2006 - 03/2003
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2006 - 08/2002
2	Messenger RNA (mRNA)IBA 03/2005 - 06/2004
2	AutoantigensIBA 10/2004 - 03/2003
1	SodiumIBA 05/2021
1	GlucocorticoidsIBA 05/2021
1	Risedronic Acid (Actonel)FDA LinkGeneric 05/2021
1	Abatacept (Orencia)FDA Link 11/2017
1	Interferon Type IIBA 03/2011
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2009
1	Codon (Codons)IBA 02/2009
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 03/2008
1	Interferon-gamma (Interferon, gamma)IBA 03/2008
1	CTLA-4 AntigenIBA 01/2008
1	Interleukin-2 (IL2)IBA 01/2008
1	InterleukinsIBA 01/2008
1	EpitopesIBA 01/2008
1	Interleukin-12 (IL 12)IBA 01/2008
1	CD40 Ligand (CD40L)IBA 01/2008
1	human GPI proteinIBA 01/2008
1	Therapeutic UsesIBA 01/2008
1	Inducible T-Cell Co-Stimulator ProteinIBA 01/2008
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 08/2007
1	Infliximab (Remicade)FDA Link 07/2007
1	Amyloid (Amyloid Fibrils)IBA 06/2007
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 06/2007
1	tocilizumab (atlizumab)FDA Link 01/2007
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2007
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2007
1	Immunoglobulin M (IgM)IBA 01/2006
1	beta 2-Glycoprotein I (Apolipoprotein H)IBA 01/2006
1	Antiphospholipid AntibodiesIBA 01/2006
1	Anticardiolipin AntibodiesIBA 01/2006
1	LigandsIBA 01/2006
1	Prothrombin (Factor II)IBA 01/2006
1	Interleukin-1beta (Interleukin 1 beta)IBA 04/2004
1	Prednisolone (Predate)FDA LinkGeneric 01/2004
1	HLA-B Antigens (HLA-B)IBA 01/2004
1	SteroidsIBA 01/2004

Therapy/Procedure

2	Therapeutics 01/2008 - 07/2007
1	Drug Tapering 11/2017
1	Injections 01/2008
1	Intravesical Administration 01/2004
1	Immunotherapy 01/2004